Thursday, September 17, 2015

Vaginal discharge


     One of the most common gynecological complaint. Has to be differentiated from physiological discharge such as in mid menstrual cycle and during pregnancy.
The natural vaginal discharge may vary considerably, especially under differing hormonal influences such as puberty, pregnancy or prescribed contraception. A sudden or recent change in discharge, especially if associated with alteration of colour and/or smell, or vulval itch/irritation is more likely to indicate an infective cause than a gradual or long-standing change.

Causative organisms:
Vaginal infection (vaginitis): 
   1.      Trichomonas Vaginalis
   2.      Bacterial vaginosis
   3.      Candida albicans

 Cervical infection (cervicitis):
   1        Neisseria gonorrhoea
   2         Chlamydia trachomatis



Clinical Features
Symptoms:
    1.      Discharge
    2.      Itching
    3.      Vaginal soreness and smell
    4.      Pain during intercourse (Dyspareunia)
Signs:
Discharge from the vaginal opening. A sequel of either vaginitis or cervicitis.
Bacterial Vaginosis, the discharge is characteristically homogeneous and off-white in colour. And vaginal pH is greater than 4.5.
Candidiasis, there may be vulval and vaginal erythema, and the discharge is typically curdy in nature. Vaginal pH is usually less than 4.5.
Trichomoniasis tends to cause a profuse yellow or green discharge and is usually associated with significant vulvovaginal inflammation.




Treatment

A. Vaginitis Treatment
                        Drug                           Dose                           Duration
}  Tinidazole                             2gm oral                     single dose
                                                                Or
          Metronidazole                        400mg oral               3/day 7 days
                                                                Plus
}  Fluconazole                          150 mg oral               single dose
                                                                 Or
         Clotrimazole                        200 mg VP                 each night for 3 nights
           

B. Cervicitis Treatment
      Drug                                            Dose                                     Duration
}  Azythromycin                             1gm oral                                 single dose
                                                                         Plus
}  Cefexime                                    400 mg oral                           single dose
                                                                           Or
             Ceftriaxone                                  250 mg IM                             single dose


Reference:
      1   .      Davidson’s principal and practice of medicine 21th edition.

      2   .      Park textbook of preventive medicine 22th edition.
  

     Related articales

     2. Vaginal discharge